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The specific muscle, the vastus lateralis, is substantial and provides a great area for the B12 solution to be absorbed

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Conditions affecting any stage of this absorption pathwayincluding pernicious anaemia (an autoimmune condition destroying intrinsic factor-producing cells), Crohn's disease, coeliac disease, or surgical removal of stomach or ileal tissuecan significantly impair B12 absorption despite its water-soluble properties

The sublingual application also provides better bioavailability by bypassing the hepatic first-pass metabolic process

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it